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Calcium supplements for enteric hyperoxaluria

What is the evidence that calcium supplementation lowers urinary oxalate in patients with post-resection enteric hyperoxaluria

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calcium supplementation lowers urinary oxalate in post-resection enteric hyperoxaluria in a dose-dependent fashion across the small studies that exist, so the direction of effect is consistent, but the data are short-term, small, and complicated by a concurrent rise in urinary calcium that partly offsets the drop in calcium-oxalate supersaturation 1,2. it works by binding dietary oxalate in the gut, and is most relevant in these patients because their baseline calcium intake and urinary calcium are typically low 1,2.

References

  1. PMID: 12474641. (metadata not in corpus)
  1. Rodgers AL, Allie-Hamdulay S, Jackson GE, Sutton RA. Enteric hyperoxaluria secondary to small bowel resection: use of computer simulation to characterize urinary risk factors for stone formation and assess potential treatment protocols. J Endourol. 2014;28(8):985-94. PMID: 24773381.

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Draft, generated by the IBDology RAG and not yet clinician-reviewed. Answers are grounded in the retrieved literature listed above; a high faithfulness score means the answer matches its sources, not that the sources are correct.

Sources retrieved: PMID 24773381 · PMID 38257157 · PMID 12474641

Reviewer notes

answered 2026-08-04 · corpus build 89548d50 · faithfulness 0.6